Tatsuo Kawai

I have more than 25-years of experience in clinical transplantation and have been working on pre-clinical and clinical research since 1991. The mixed chimerism approach established for the renal allograft tolerance in nonhuman primates has been successfully translated to clinical kidney transplantation (reported in NEJM in 2008). My current research has been directed towards developing a more clinically feasible protocols for immunological tolerance induction, which has been translated to clinical kidney transplantation. Another research interest has been kidney xenotransplantation. In collaboration with eGenesis, kidney xenograft survival exceeding 2 years has been achieved (Anand et al. Nature 2023). Based on this preclinical study, I recently conducted kidney xenotransplantation in a living patient with ESRD, using kidney xenograft with triple knockout of major xenogeneic antigens, PERV knockout and seven human transgenes.

15th August 2025

Time	Session

08:30 10:00	Plenary Session 2-1 Overview and Recent Advancement of Renal Xenotransplantation Ho-Yee TiongSingapore Moderator Tatsuo KawaiUnited States Speaker Genetic Testing in the Evaluation of Recipient Candidates and Living Kidney Donor Brian K. LeeUnited States Speaker How to Build Up a Strong Kidney Transplant Program with Continuing Growth? Cheng-Kuang YangTaiwan Moderator Alvin WeeUnited States Speaker Recent Advances in ED: Bridging Innovation and Clinical Practice Wei-Kung TsaiTaiwan Moderator Tom LueUnited States Speaker Penile Fibro-Voruilon Assembly and Venours Stripping Surgery for ED Mohamed Salim Al-MarhoonOman Moderator Geng-Long HsuTaiwan Speaker Male Infertility: Challenges and Opportunities in Asia Norio NonomuraJapan Moderator William J. HuangTaiwan Speaker TICC - 3F Banquet Hall
10:30 12:00	Transplant (TBC) (TBC) Brian K. LeeUnited States Speaker (TBC) Tatsuo KawaiUnited States Speaker (TBC) Alvin WeeUnited States Speaker TICC - 2F 201DE