Testis cancer is the most common tumor detected in men aged from 20 to 35 years accounting for 1-2%. About 20-30% of patients are presenting with pure seminoma of the testis. We would present our experience of synchronous and metachronous bilateral testicular seminoma in recently over 30 years.

This is a review article. The episode happened in 30 years ago. A 28 years old male patient was suffered from abdominal pain because of intestinal obstruction. The emergency operation was performed and revealed a huge mass in right lower pelvic cavity causing intestinal obstruction. The huge mass was an undescended right testis tumor with intra-peritoneum carcinomatosis with lymph nodes metastasis. There was also a protruding mass over left inguinal area simultaneously. The pathology revealed pure seminoma of both testes. The other patient was a 26 years old young man. He was found to be pure seminoma in 2011 and was performed left radical orchiectomy and then complete course of chemotherapy. He followed up the tumor markers and image study every 6 months or one year. The metachronous seminoma of right testis was diagnosed in 2023.

The patient with synchronous undescended testes seminoma died of disease within 6 months in spite of appropriate treatment 30 years ago. The other patient of bilateral metachronous testicular seminoma attacked over the contra-lateral testis 12 years after previous one. The patient was performed radical orchiectomy and adjuvant chemotherapy with BEP. He was reconstructed with both testes prosthesis for cosmetic and psychological reasons after the consequent condition stable.

The incidence of bilateral seminoma was related to the histological type of the initial tumor. These findings have potentially important implications for clinical management by identifying a population of patients with seminoma who are at risk of developing a second tumor. It also suggests a recent increase in incidence of bilateral testicular tumors as possibly related to improved treatment modalities with a higher cure rate of the original seminoma.