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Abstract
Abstract Title
The Success Rate of Direct Vision Internal Urethrotomy for Patients with Urethral Strictures: A Local Setting, Retrospective Review, A 2024 Update.
Presentation Type
Podium Abstract
Manuscript Type
Clinical Research
Abstract Category *
Functional Urology: Reconstructive Surgery
Author's Information
Number of Authors (including submitting/presenting author) *
3
No more than 10 authors can be listed (as per the Good Publication Practice (GPP) Guidelines).
Please ensure the authors are listed in the right order.
Country
Philippines
Co-author 1
Josemarie Emmanuel Roxas roxasjem10@gmail.com University of Santo Tomas Hospital Urology Manila Philippines *
Co-author 2
Janssen Dion Unas janssenunas@gmail.com University of Santo Tomas Hospital Urology Manila Philippines -
Co-author 3
Mark Joseph Abalajon totoabalajon@yahoo.com University of Santo Tomas Hospital Urology Manila Philippines -
Co-author 4
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Co-author 5
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Co-author 6
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Co-author 7
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Co-author 8
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Co-author 9
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Co-author 10
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Co-author 11
Co-author 12
Co-author 13
Co-author 14
Co-author 15
Co-author 16
Co-author 17
Co-author 18
Co-author 19
Co-author 20
Abstract Content
Introduction
Direct Vision Internal Urethrotomy (DVIU) is the most common management for patients with urethral stricture disease (USD) in the Philippines, owing to its ease of performance and short convalescence. This study aims to show the success rate of DVIU in the treatment of male urethral strictures in the local setting and, can be an index study that could be a basis for future management of urethral stricture disease in the Philippines.
Materials and Methods
A retrospective review was done from January 1995 to September 2024 on patients who underwent DVIU. Patients who underwent radiation therapy, with a history of previous open urethral surgery (e.g. urethroplasty and hypospadias repair), and those who were diagnosed with bladder neck contracture, were excluded from the study. The stricture-free rate following the first to third DVIU procedures was analyzed using the Kaplan-Meier method.
Results
138 patients were included in the analysis, wherein the stricture-free rate was noted to be 21.7% (n = 30). The mean time to recurrence was 16 months, ranging from 3 weeks to 96 months, after the first DVIU. 38 patients (28%) had a second DVIU, with stricture-free rates of 0% with a mean time to recurrence of 21 months, ranging from 2 weeks to 120 months. 12 patients (8%) underwent a third DVIU with 0% stricture-free rates, with a 14-month mean time to recurrence, with a range of 1 week to 36 months. The initial mean stricture length was 1.8 cm (0.5 - 7.5cm) and the mean stricture length at the time of recurrence, post-first DVIU, was 3cm (1.5 - 8cm) which was statistically significant (p <0.001). A total of 58 patients had early recurrence. In patients with strictures >2cm in length, 70% (39 patients) had early recurrence, in contrast to patients with <2cm, only 29% recurred within 12 months (P = 0.005). 25 patients had penile urethral strictures. 50% (n = 12) of which had early recurrence. Of note is that the single instance of urethral diverticulum, and 2 out of the 4 urethrocutaneous fistula were found in this subgroup.
Conclusions
In the local setting, the overall success rate of direct vision internal urethrotomy is poor for patients with USD. The stricture stricture-free rate of an initial DVIU is only 21.7%, while subsequent DVIUs demonstrated a 100% stricture recurrence rate. DVIUs performed for strictures >2cm and located in the penile urethra are observed to have more complications and early recurrences. Furthermore, recurrences after DVIU are longer and more complex than the initial presentation. Urethroplasty might be a more valid option for USD with DVIU as a temporary measure before definitive treatment. To our knowledge, this is the first such study in the Philippines to describe DVIU success rates over medium-term follow-up.
Keywords
Urethral Stricture Disease, Direct Vision Internal Urethrotomy, Stricture Free Rate
Figure 1
https://storage.unitedwebnetwork.com/files/1237/9f8dedffcfdd7c0da72dd9a6dfd7332e.png
Figure 1 Caption
Kaplan-Meier Stricture-Free curves
Figure 2
https://storage.unitedwebnetwork.com/files/1237/8603be3c7e544c0ac3fb6191f6dd3232.png
Figure 2 Caption
Patient Demographics
Figure 3
https://storage.unitedwebnetwork.com/files/1237/5bec7779a01845a3646611e7872e57b9.png
Figure 3 Caption
Table 2. Results of DVIU from 1st to 3rd; Table 3. Early stricture recurrence
Figure 4
Figure 4 Caption
Patients with Penile stricture
Figure 5
Figure 5 Caption
Character Count
2015
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