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Abstract

Abstract Title

Evaluation of Cystography/Voiding Cystourethrography Prior to Renal Transplantation: A Systematic Review and Meta Analysis

Presentation Type

Moderated Poster Abstract

Manuscript Type

Meta Analysis / Systematic Review

Abstract Category *

Transplantation

Author's Information

Number of Authors (including submitting/presenting author) *

No more than 10 authors can be listed (as per the Good Publication Practice (GPP) Guidelines).
Please ensure the authors are listed in the right order.

Co-author 1

Kyousuke Kamiya ken.kamiya@yahoo.com National Kidney and Transplant Institute Urology Quezon City Philippines *

Co-author 2

Jose Benito Abraham drjbabraham@gmail.com National Kidney and Transplant Institute Urology Quezon City Philippines -

Co-author 3

Ernesto Gerial Jr jungerial@yahoo.com National Kidney and Transplant Institute Urology Quezon City Philippines -

Co-author 4

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Co-author 7

Co-author 8

Co-author 9

Co-author 10

Co-author 11

Co-author 12

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Co-author 16

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Co-author 20

Abstract Content

Introduction

Invasive procedures such as cystography or voiding cystourethrography have been used by different centers for pre-transplant assessment of bladder capacity and other abnormalities. However, it has a low pick up rate for urologic disease if the patient does not have any past urologic abnormality and the low volume bladder of these oligoanuric patients can increase its capacity post transplantation as long as it is previously healthy. The purpose of this meta-analysis was to establish if pre-operative cystography or VCUG is necessary for every ESRD patient undergoing kidney transplantation.

Materials and Methods

The study included all comparative studies published until June 2024 which compared cystography/VCUG findings on ESRD patients without previous urologic abnormality versus those with urologic abnormality/previous history of urologic disease.

Results

Five studies were included and the overall incidence rate of abnormal findings in patients without urologic abnormality was 4.8% (43/902). On the other hand, the overall incidence rate of abnormal findings in patients with urologic abnormality was 45.4% (127/280). The overall Risk Ratio showed significantly lower incidence rate of abnormal findings in non- urologic history of disease than urologic cases (RR=0.07, 95% CI=0.02 to 0.29, p=0.0003).

Conclusions

Our findings suggest pre-kidney transplant VCUG is not necessary for ESRD patients The study suggest pre-kidney transplant VCUG is not necessary for ESRD patients who have no previous or current urologic abnormalities.

Keywords

voiding cystourethrography, kidney transplant, bladder capacity, urologic abnormalities

Figure 1

https://storage.unitedwebnetwork.com/files/1/dbd057e36b42bbd59214195351704b24.png

Figure 1 Caption

Figure 1. PRISMA flow chart showing the study selection process for meta-analysis

Figure 2

https://storage.unitedwebnetwork.com/files/1/2586ccbd326e0f625c0c4c5cdf6d554a.png

Figure 2 Caption

Figure 2. Forest plot on the incidence rates of abnormal findings between those with and without urologic abnormality/history of urologic disease

Figure 3

https://storage.unitedwebnetwork.com/files/1/859a408e9fc434fa207749a0b31ed1c1.png

Figure 3 Caption

Figure 3. Sub-group analysis by age-group on the incidence rates of abnormal findings between those with and without urologic abnormality/history of urologic disease

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Presentation Order