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Abstract
Abstract Title
Modeling of Extracorporeal Shock Wave Lithotripsy Outcomes in Pediatric Urolithiasis: A 15-Year Analysis of 326 Cases
Presentation Type
Moderated Poster Abstract
Manuscript Type
Clinical Research
Abstract Category *
Endourology: Urolithiasis
Author's Information
Number of Authors (including submitting/presenting author) *
4
No more than 10 authors can be listed (as per the Good Publication Practice (GPP) Guidelines).
Please ensure the authors are listed in the right order.
Country
China
Co-author 1
zhou peng 13616555138@139.com the third people's hospital of hangzhou city Urology hangzhou China *
Co-author 2
gong xiuqing 2579820631@qq.com the third people's hospital of hangzhou city urology hangzhou China
Co-author 3
lou yangfeng cwgebao@126.com the third people's hospital of hangzhou city urology hangzhou China
Co-author 4
yang longfei 2508105842@qq.com the third people's hospital of hangzhou city urology hangzhou China
Co-author 5
Co-author 6
Co-author 7
Co-author 8
Co-author 9
Co-author 10
Co-author 11
Co-author 12
Co-author 13
Co-author 14
Co-author 15
Co-author 16
Co-author 17
Co-author 18
Co-author 19
Co-author 20
Abstract Content
Introduction
Extracorporeal Shock Wave Lithotripsy (ESWL) remains a cornerstone non-invasive modality for managing pediatric urolithiasis, leveraging focused acoustic energy to fragment calculi. This study evaluates the efficacy and predictive utility of the Dogan and Onal scoring systems in a 15-year cohort of 326 pediatric patients, contextualized within contemporary AUA and EAU recommendations for optimizing ESWL outcomes.
Materials and Methods
Between 2009 and 2024, 326 children (aged 1-18 years) underwent ESWL using a third-generation Hydroelectric lithotripter, delivering 2000-3000 shock waves per session at 65 pulses per minute. Stone localization was achieved via ultrasonography. Dogan and Onal scores were derived from stone characteristics (size, location) and patient variables (age, BMI, skin-to-stone distance). Treatment success was defined as stone-free status or residual fragments <4mm at 3 months post-procedure, per EAU criteria; failure encompassed residuals ≥4mm or the need for auxiliary interventions. Statistical analysis employed logistic regression to assess score-outcome associations, with receiver operating characteristic (ROC) curves quantifying predictive accuracy.
Results
The cohort had a mean age of 9.7 years, with 58% male patients (n=189/326). Calculi distribution included renal pelvis (45%), proximal ureter (30%), and other sites (25%). The stone-free rate was 72% (n=235/326), with 18% (n=59/326) exhibiting clinically insignificant residuals and 10% (n=32/326) classified as failures—consistent with AUA-reported efficacy rates of 70-90% for stones <20mm. Stratified by Dogan score, patients with scores <2 achieved an 85% success rate (111/130), declining to 45% (15/33) for scores >4. For Onal scores, success was 82% (161/196) at <3, dropping to 25% (8/32) at >5. Logistic regression confirmed significant predictive power for both Dogan (odds ratio [OR]=0.72, 95% CI 0.65-0.80, P<0.001) and Onal (OR=0.68, 95% CI 0.61-0.76, P<0.001) scores. ROC analysis yielded an area under the curve (AUC) values of 0.78 for Dogan and 0.75 for Onal, with no statistically significant difference in discriminatory capacity (P=0.23), aligning with predictive models in recent literature.
Conclusions
ESWL demonstrates robust efficacy in pediatric urolithiasis, with a 72% stone-free rate corroborated by contemporary AUA/EAU benchmarks. The Dogan and Onal scoring systems offer reliable preoperative prognostication, with lower scores portending superior outcomes. Comparable AUCs (0.78 and 0.75) underscore their utility as validated tools. Adherence to optimized protocols—such as reduced shock wave frequency and enhanced targeting—may further elevate success rates, supporting their integration into clinical decision-making for pediatric stone management.
Keywords
Pediatric urolithiasis, Extracorporeal Shock Wave Lithotripsy, Dogan score, Onal score, Predictive modeling
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