Giggle incontinence is a form of urinary incontinence triggered by laughter, predominantly affecting children. This condition can significantly impact social and emotional well-being. Understanding the effectiveness of various treatment modalities is essential for optimal management.To compare the efficacy of medical and non-medical treatments for giggle incontinence in a cohort of 14 children, examining differences in outcomes between girls and boys.

A case series of 14 patients diagnosed with giggle incontinence was analyzed. Patients were divided into two groups: those receiving medical treatment (e.g., anticholinergics, desmopressin) and those undergoing non-medical interventions (e.g., bladder training, pelvic floor exercises). Treatment outcomes were assessed based on frequency of episodes, patient-reported quality of life, and parental satisfaction.

Medical Treatment: Among the 7 patients receiving medical therapy, a 50% reduction in episode frequency was observed in 4 cases, with significant improvement in quality of life reported by parents.Non-Medical Treatment: The 7 patients undergoing non-medical interventions experienced a 70% reduction in episodes, with higher parental satisfaction noted. Gender Comparison: Girls showed a slightly higher response rate to non-medical treatments, while boys benefited more from medical therapies, though results were not statistically significant.

Both medical and non-medical treatments are effective in managing giggle incontinence, with non-medical approaches showing slightly superior outcomes in this small cohort. Further studies with larger sample sizes are needed to validate these findings and explore gender-specific responses to treatment.