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Abstract
Abstract Title
Hope Through Surgery, Pursuing Cure After Rising tumor markers
Presentation Type
Moderated Poster Abstract
Manuscript Type
Case Study
Abstract Category *
Oncology: Urethra/ Penis/ Testes/ Sarcoma/ Miscellaneous
Author's Information
Number of Authors (including submitting/presenting author) *
4
No more than 10 authors can be listed (as per the Good Publication Practice (GPP) Guidelines).
Please ensure the authors are listed in the right order.
Country
India
Co-author 1
Rajath S Shetty Rajath.shetty10@gmail.com AIIMS NEW DEHLI UROLOGY NEW Delhi India *
Co-author 2
BALAGOLA ADINARAYAN aadiikmck2k09@gmail.com AIIMS NEW DEHLI UROLOGY NEW Delhi India -
Co-author 3
NITISH AGARWAL NITISHAGARWAL@GMAIL.COM AIIMS NEW DEHLI UROLOGY NEW Delhi India -
Co-author 4
AMLESH SETH amlesh.shetty10@gmail.com AIIMS NEW DEHLI UROLOGY NEW Delhi India -
Co-author 5
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Co-author 9
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Co-author 10
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Co-author 11
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Co-author 14
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Co-author 20
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Abstract Content
Introduction
Non-seminomatous germ cell tumors of the testis are highly curable, yet a subset of patients have persistent elevation of serum tumor markers (STMs) despite optimal chemotherapy. Desperation retroperitoneal lymph node dissection RPLND is considered in such cases, especially when disease progresses despite multiple lines of systemic therapy.
Materials and Methods
A 28-year old with NSGCT underwent right high inguinal orchidectomy in 2020, f/b 4 cycles of BEP chemotherapy. After a 3.5-year remission, he had rising AFP levels (5910 ng/mL) and radiological progression of retroperitoneal lymph nodes and lung nodules. He received TIP and Gem-Ox chemotherapy without sustained response
Results
Surgery was uneventful, and he was discharged on POD 4. HPE-Mature teratoma and yolk sac tumor components. Postoperative tumor markers declined.
Conclusions
Desperation RPLND can offer disease control in few patients with chemo-refractory NSGCT. Careful patient selection, surgical expertise and multidisciplinary approach are essential for outcomes.
Keywords
Figure 1
https://storage.unitedwebnetwork.com/files/1237/b8bbfaeacb7eccd6e5b2f236d7e3f9e4.jpeg
Figure 1 Caption
image at intial presentation
Figure 2
https://storage.unitedwebnetwork.com/files/1237/d29d27b4940e72796bbc233f5fc13050.jpeg
Figure 2 Caption
immediately post chemo
Figure 3
https://storage.unitedwebnetwork.com/files/1237/2d7ee9e31cb21363fbc2866c04c2ce37.jpeg
Figure 3 Caption
Image post salvage chemo
Figure 4
https://storage.unitedwebnetwork.com/files/1237/b59131a2d6221fc5216b1306f9268bde.jpeg
Figure 4 Caption
surgical specimen
Figure 5
Figure 5 Caption
Character Count
3000
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