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Submitted
Abstract
Laser Analysis for Stone Treatment (LAST): An Ex-Vivo Comparative Study of Magneto Holmium:YAG and Fiber Dust Thulium Fiber Lasers: Primary Effects on Ablation, Propulsion, Fragmentation, and Heat Generation Using Phantom Urologic Stones
Podium Abstract
Basic Research
Endourology: Urolithiasis
Author's Information
6
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Philippines
Karl Marvin Tan kmtanmd@gmail.com Veterans Memorial Medical Center Department of Urology Quezon City Philippines -
Alfonso Victor Luna vluna.md@gmail.com Veterans Memorial Medical Center Department of Urology Quezon City Philippines *
John Christopher Sta Ana jcgstaana@gmail.com Veterans Memorial Medical Center Department of Urology Quezon City Philippines -
Vineet Gauhar vineetgaauhaar@gmail.com Ng Teng Fong General Hospital Department of Urology Singapore Singapore -
Steffi Kar Kei Yuen steffiyuen@surgery.cuhk.edu.hk Chinese University of Hong Kong Department of Surgery Hong Kong Hong Kong, China -
Olivier Traxer traxer.olivier@gmail.com Progressive Endourological Association for Research and Leading Solutions (PEARLS) Paris France -
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Abstract Content
This ex-vivo study aims to compare the retropulsion, fragmentation efficiency, heat generation and crater generation of MAGNETO Ho:YAG using three pulse modulation settings: The standard, MAGNETO setting, Virtual Basket setting, and comparing with Thulium Fiber using both short and long pulse laser settings, in gypsum-based phantom stones at three energy levels (0.5J, 1J, and 2J) and 2 types of laser (200µm and 550µm). Aim is to compare which laser and settings are best for the lithotripsy of urinary stones for clinical application.
Gypsum (100g) and water (50mL) mixture cured forming stones 0.5cm square dimension. Quanta System MAGNETO Holmium-YAG Laser (Cyber Ho 150W Magneto) and Thulium Fiber Laser (TFL) Tools: High-speed camera for capturing retropulsion, Acrylic water bath box stone immersion with laser access, Digital thermometer
Retropulsion: TFL (Short pulse) and Ho:YAG Magneto demonstrated slightly more consistent and reduced retropulsion trends. Ablation efficiency: TFL Short pulse had significant higher ablation efficiency than Ho:YAG Standard and Virtual Basket. Heat generation: TFL Long pulse had significant higher temperature than all Ho:YAG settings. TFL Short noted more heating than Ho:YAG Standard Fragmentation time: TFL Short and Ho:YAG MAGNETO significant reduced fragmentation time compared to Ho:YAG Standard. Laser efficacy: TFL Short pulse had significant greater efficacy than all Ho:YAG modes.
The Ho:YAG MAGNETO setting is superior for stone treatment. TFL had high ablation efficiency and fragmentation speed, but greater thermal rise, potential for safety concerns in clinical application. The Ho:YAG MAGNETO setting balances performance and safety, with faster fragmentation time than both TFL long and Ho:YAG standard modes, competitive ablation efficiency similar to TFL short, but less heat generation observed with TFL. Findings support Ho:YAG Magneto as an optimized laser setting that bridges efficacy and safety for clinical laser lithotripsy.
Magneto, Holmium, TFL, Gypsum stones
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Measurement of stone retropulsion
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Measurement of stone fragmentation/dusting and heat generation
 
 
 
 
 
 
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