Prostatic calculi (PC) have garnered increasing attention with advancements in diagnostic tools such as transrectal ultrasound (TRUS) and CT scans. Studies show a significant association between prostatic calculi and lower urinary tract symptoms (LUTS), which affect 50-70% of men over 50. Additionally, prostatic calculi have been linked to erectile dysfunction (ED), chronic prostatitis, and often co-occur with chronic pelvic pain. In this study, we aim to explore the relationship between prostatic calculi and urodynamic changes before and after anatomical endoscopic enucleation of the prostate.

This retrospective study focuses on patients aged 45 to 95 who underwent anatomical endoscopic enucleation for benign prostatic hyperplasia (BPH) between 2019 and 2020 at a single medical center, all performed by a single surgeon. Patient data were collected from medical records. Prostatic calculi were diagnosed using transrectal ultrasound (TRUS). Patients were divided into two groups based on the proportion of prostatic calculi in the boundary of peripheral and transitional zones of the prostate (>50% and <50%). We compared pre-operative and post-operative urodynamic data between these groups. Statistical analysis employed paired t-tests and Fisher's exact tests as primary methods.

216 patients were included in the study, out of which 154 were diagnosed with prostatic calculi through TRUS, and had complete urodynamics study both before and 1.5 months after surgery. The group with more prostatic calculi exhibited significantly lower voiding volume (VV) after surgery compared to the group with fewer calculi. Additionally, the presence of more prostatic calculi showed no improvement in VV after operation.

Prostatic calculi have been associated with changes in voiding volume (VV), suggesting a potential impact on bladder function. However, further studies are necessary to clarify these associations and understand the underlying mechanisms.