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Non-Moderated Poster Abstract

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Abstract

Abstract Title

A novel portable integrated magneto-electrochemical platform for prostate cancer detection

Presentation Type

Moderated Poster Abstract

Manuscript Type

Clinical Research

Abstract Category *

Oncology: Prostate

Author's Information

Number of Authors (including submitting/presenting author) *

No more than 10 authors can be listed (as per the Good Publication Practice (GPP) Guidelines).
Please ensure the authors are listed in the right order.

Co-author 1

Jui-Ming Liu mento1218@gmail.com Taoyuan General Hospital, Ministry of Health and Welfare Department of Urology Taoyuan Taiwan *

Co-author 2

Ren-Jun Hsu hsurnai@gmail.com Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation Cancer Research Center Hualien Taiwan -

Co-author 3

Chen-Han Huang chhuang@ncu.edu.tw National Central University Department of Biomedical Sciences and Engineering Taoyuan Taiwan -

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Abstract Content

Introduction

Prostate cancer (PCa) remains a global health concern, frequently undetected until advanced stages. Novel approaches to Prostate-Specific Antigen (PSA) screening are essential to improve early detection

Materials and Methods

We developed a magneto-electrochemical biosensor designed for sensitive PSA detection in complex biological samples. This study assessed its performance in detecting PSA across various media derived from prostate cell cultures. Prostate cancer cell lines LNCaP and PC3, and non-cancerous prostate cell line PZ-HPV-7, were cultured in RPMI-1640, Ham’s F12K, and keratinocyte-serum-free media. PSA levels were then measured using the biosensor, with results compared to those from a standard commercial PSA kit to determine efficacy and sensitivity.

Results

The biosensor successfully detected PSA in all media, yielding results comparable to commercial standards.

Conclusions

This biosensor presents a sensitive and efficient tool for PSA detection, enhancing prostate cancer diagnostics.

Keywords

Biosensor, PSA, Prostate

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