Varicocele is a collection of abnormally dilated tortuous spermatic veins. Most varicoceles are left-sided, and the left-sided predominance is explained by turbulent venous flow related to the right-angle insertion of the left testicular vein into the left renal vein. The prevalence of varicocele is reported as high as 10-15% in the general population, 30-35% in men with primary infertility, and 69-81% in men with secondary infertility.

All patients who fulfilled the inclusion criteria and visited to LNH&MC,Karachi were included in the study after taken informed consent. In our study, semen sample was obtained from the patients and sent to laboratory to assess parameters of abnormal semen.

Mean ± SD of age was 40.3±17.1 with C.I (37.54…….43.05) years. Grade of varicocele showed that, 15 (10.0%) patients noted with grade O, grade-I was documented in 21 (14.0%), grade II in 36 (24.0%) while grade III was noted in 78 (52.0%). In distribution of abnormal semen parameters, oligozoospermia was noted in 95 (63.4%) patients, asthenozoopermia in 80 (53.4%), teratozoospermia 33 (22.0%) while azoospermia was found to be in 16 (10.7%) patients.

It is to be concluded that oligozoospermia was found to be the most common parameter of abnormal semen in patients with varicocele followed by asthenozoopermia and teratozoospermia. The sample population represents a single institutional experience; but the study sample can be generalized as the sample came from various areas of Pakistan.