- UAA Congress 2025

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Podium Abstract

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Presentation Date / Time

Submission Status

Submitted

Abstract

Abstract Title

A 10-year single center experience review of partial cystectomy from 2014 to 2024

Presentation Type

Podium Abstract

Manuscript Type

Clinical Research

Abstract Category *

Oncology: Bladder and UTUC

Author's Information

Number of Authors (including submitting/presenting author) *

5

No more than 10 authors can be listed (as per the Good Publication Practice (GPP) Guidelines).
Please ensure the authors are listed in the right order.

Country

Taiwan

Co-author 1

Ting Lien Li ccvb123456tw@gmail.com China Medical University Hospital Urology Taichung Taiwan *

Co-author 2

Chao Shiang Chang 008395@tool.caaumed.org.tw China Medical University Hospital Urology Taichung Taiwan -

Co-author 3

Chi Ping Huang 017561@tool.caaumed.org.tw China Medical University Hospital Urology Taichung Taiwan -

Co-author 4

Ching Chung Yeh 001436@tool.caaumed.org.tw China Medical University Hospital Urology Taichung Taiwan -

Co-author 5

Chi Ray Yang 008657@tool.caaumed.org.tw China Medical University Hospital Urology Taichung Taiwan -

Co-author 6

Co-author 7

Co-author 8

Co-author 9

Co-author 10

Co-author 11

Co-author 12

Co-author 13

Co-author 14

Co-author 15

Co-author 16

Co-author 17

Co-author 18

Co-author 19

Co-author 20

Abstract Content

Introduction

Partial cystectomy (PC) is a bladder-sparing treatment option for bladder cancer, intended for a carefully selected group of patients. Neoadjuvant therapy has gained popularity in recent years, and immunotherapy as a neoadjuvant treatment has shown promising results in cancer control. This study aimed to evaluate the outcomes of PC in a recent cohort of patients treated at a single institution.

Materials and Methods

Medical records were reviewed for 39 patients diagnosed with primary urothelial carcinoma (UC) who underwent partial cystectomy with curative intent at China Medical University Hospital between 2013 and 2024. The primary endpoints included noninvasive recurrence (defined as any recurrence of non-muscle invasive disease), advanced recurrence (defined as muscle-invasive recurrence or metastasis), and mortality. Unadjusted Cox proportional hazards regression and log-rank tests were employed to assess associations between clinical characteristics and these endpoints.

Results

In a cohort of 39 patients with bladder cancer treated by partial cystectomy, the median age was 75.8 years (interquartile range 45-91), with 69% male patients. Preoperative neoadjuvant chemotherapy (NAC) was administered to 54% of patients. Pathologic staging revealed that 62% had tumors classified as

Conclusions

In well-selected patients, partial cystectomy provides adequate local control of bladder cancer. Neoadjuvant therapy may improve patient survival. The risk of systemic progression is comparable to that reported in case series of radical cystectomy."

Keywords

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Presentation Order

15