Robot-assisted laparoscopic surgery has been increasingly applied in retroperitoneal tumor (RPT) resection due to its precision and minimally invasive approach. This study aims to report the initial experience and clinical outcomes of robot-assisted laparoscopic RPT resection performed by a single surgeon at Binh Dan Hospital.

A retrospective review of 8 patients who underwent robot-assisted laparoscopic RPT resection from 2020 to 2024 was conducted. Data on demographics, tumor characteristics, perioperative outcomes, and pathology were analyzed.

Median patient age was 45 years (range: 21–76), and tumor size ranged from 49 to 160 mm (median: 65 mm). 87.5% of tumors were benign. The median operative time was 150 minutes (range: 60–240), with a median blood loss of 100 mL (range: 20–800). There were no conversions to open surgery. One intraoperative complication involving renal vein injury was successfully managed. Postoperative complications occurred in one case (12.5%) (Clavien-Dindo II). The median length of hospital stay was 5.5 days, with all patients achieving negative surgical margins.

Robot-assisted laparoscopic resection of RPT is a feasible approach with encouraging initial outcomes. However, larger, multi-center studies are needed to further evaluate its safety and efficacy in broader clinical applications.