This session provides a structured overview of current interventional treatment options for nephrolithiasis using laser lithotripsy. Focus is placed on the clinical significance of residual stone fragments, which remain a major concern due to their association with recurrence and complications. The innovative mediNiK hydrogel for removal of stone fragments is introduced with clinical trial results demonstrating its
feasibility and therapeutic promise in achieving a stone-free patient. Additionally, initial findings demonstrate that the combined use of mediNiK with suction devices results in effective synergies.